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• April 9, 2025 Webinar - Autoimmune Hemolytic Anemia: New Insights from Preclinical Models

  • When
    Wednesday, April 09, 2025
  •  
    3:00 PM - 4:00 PM
  • Location
    Online
  • Spaces left
    75

  Register

  Wednesday, April 9, 2025 / 3:00 PM - 4:00 PM EDT

  Topic:
  Autoimmune Hemolytic Anemia: New Insights from Preclinical Models

  

  Speaker:
  Krystalyn E. Hudson, PhD
  Columbia University

  Speaker Bio:

  Dr. Krystalyn E. Hudson is an Associate Professor at Columbia University and Co-Director of the Laboratory of Transfusion Biology. She received her PhD from Emory University and completed her postdoctoral fellowship at Scripps Research Institute. Dr. Hudson’s NIH funded research focuses on immune responses to red blood cells (RBCs), which is relevant for transfusion medicine, pregnancy, and transplantation. Her team developed two new innovative preclinical murine models of autoimmune hemolytic anemia (AIHA); these models led to the discovery of a 3-week tolerization window for RBC autoreactive T cells, identified a new T cell subset that predicts tolerance failure and AIHA onset, and revealed new therapeutic targets.

  
  

  Abstract:
  

  Autoimmune hemolytic anemia is the most frequently reported immune-related adverse event to checkpoint inhibitor immunotherapy. To elucidate the mechanistic underpinnings leading to AIHA, we developed a new preclinical model. This session will discuss findings from this model, highlighting discovery of a new biomarker that predicts AIHA onset and a novel therapeutic target.

  
  Objectives:

  1. Describe a new preclinical model of AIHA
     
  2. Discuss a new cell subset that can be used to predict AIHA
  3. Describe a new AIHA treatment option

  Disclosures:

  None

  Pricing:

  • Members: FREE (Registration is required.)
  • Non-Members: $45 per session & $130 entire series
  • Institutions: $75 per session & $200 entire series

  To receive member pricing, be sure to sign in.

  
  Upcoming Webinars:
  March 12, 2025 Webinar - Creating A Culture of Patient Blood Management Within An Organization: The Blood Bank as a Catalyst for Change
  Watch for additional sessions in our Spring Webinar Series coming soon!
  
  

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• May 14, 2025 Webinar - Providing ABO-Matched Blood Products for CAR-T Patients

  • When
    Wednesday, May 14, 2025
  •  
    3:00 PM - 4:00 PM
  • Location
    Online
  • Spaces left
    75

  Register

  Wednesday, May 14, 2025 / 3:00 PM - 4:00 PM EDT

  Topic:
  Providing ABO-Matched Blood Products for CAR-T Patients

  

  Speaker:
  Nicholas Tong, MD
  Transfusion Medicine Fellow
  University of Rochester Medical Center

  Speaker Bio:

  Dr. Tong completed his AP/CP pathology residency at Northwell Health at North Shore University Hospital and Long Island Jewish Medical Center in June 2024. He is currently the Transfusion Medicine Fellow at University of Rochester Medical Center.

  
  

  Abstract:
  

  Chimeric antigen receptor (CAR) T-cell therapy was first approved by the Food and Drug Administration (FDA) in 2017 for the treatment of acute lymphoblastic leukemia in children, and since then other versions have been approved to treat adults with diseases such as non-Hodgkin lymphoma and multiple myeloma. Some reports in the literature have shown increased bleeding and reduced time in remission with the transfusion of blood products. Attendees of this webinar will learn how the University of Rochester Medical Center (URMC) manages transfusion support for its patients who receive CAR-T therapy. The session will highlight the benefits of the avoidance of infusing ABO mismatched antigen and antibody and as well as washing blood products for CAR-T recipients.
  

  
  Objectives:
  

  1. Describe the possible complications associated with CAR-T cell therapy
  2. Discuss the benefits of transfusing ABO-matched blood products, including platelets, to patients in general and in the context of CAR-T cell therapy
  3. Analyze the potential benefits of washing blood products for patients receiving CAR-T cell therapy

  Disclosures:

  None

  Pricing:

  • Members: FREE (Registration is required.)
  • Non-Members: $45 per session & $130 entire series
  • Institutions: $75 per session & $200 entire series

  To receive member pricing, be sure to sign in.

  
  Upcoming Webinars - register now!
  March 12, 2025 Webinar - Creating A Culture of Patient Blood Management Within An Organization: The Blood Bank as a Catalyst for Change
  April 9, 2025 Webinar - Autoimmune Hemolytic Anemia: New Insights from Preclinical Models
  
  

  Show details