BBANYS Feb 11, 2026 Webinar - Clinical Decision Making: Transfusing Patients with Red Cell Antibodies

Wednesday, February 11, 2026 / 3:00 PM - 4:00 PM EST

Topic:
Clinical Decision Making: Transfusing Patients with Red Cell Antibodies

Spring Webinar Series - Mark Your Calendar:
Subsequent webinars in our series will be held
March 11 and April 8, all at 3 pm EDT

Speaker:
Tayler Van Denakker, MD
Assistant Director of Blood Bank and Transfusion Services
Mount Sinai Hospital
Department of Pathology

Speaker Bio:
Dr. Tayler Van Denakker is currently assistant professor of pathology and assistant medical director of the blood bank and transfusion services at Mount Sinai Hospital in New York. She completed her residency in anatomic and clinical pathology at Mount Sinai followed by fellowships in hematopathology at Weill-Cornell Medical Center and transfusion medicine at Johns Hopkins Hospital.

Abstract:
Transfusion of patients with red cell antibodies poses significant clinical and laboratory challenges requiring individualized decision-making. This presentation reviews the immunologic mechanisms of alloimmunization, including antigen- and recipient-related risk factors, and examines the clinical consequences of antibody formation. Case-based examples highlight delayed hemolytic transfusion reactions, hyperhemolysis syndrome, hemolytic disease of the fetus and newborn, and passenger lymphocyte syndrome. Special populations such as patients with sickle cell disease, pregnant patients with alloantibodies, individuals receiving anti-CD38 therapy, and those with rare or high-frequency antigen antibodies are discussed. Practical strategies for blood selection, transfusion risk mitigation, and alternatives to transfusion are emphasized.

Objectives:

1. Discuss how and why different patients make antibodies
2. Discuss how to transfuse patients with antibodies in various clinical scenarios
3. Understand unique transfusion considerations in sickle cell disease.

Disclosures:
None

Pricing:

• Members: FREE (Registration is required.)
• Non-Members: $45 per session & $130 entire series
• Institutions: $75 per session & $200 entire series

To receive member pricing, be sure to sign in.

View our calendar of upcoming events, including the 2026 Spring Webinar Series and Journal Club opportunities!
www.bbanys.org/events